The average bus between 59th St. and New York Penn Station takes 21h 25m and the fastest bus takes 20h 32m. There is at least one bus per day from 59th St. to New York Penn Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between 59th St. and New York Penn Station. The earliest departure is at 6:17 AM in the morning, and the last departure from 59th St. is at 5:34 PM which arrives into New York Penn Station at 4:25 PM. All services require a transfer at Union Station Transit Center and take an average of 21h 25m. The schedules shown below are for the next available departures.
Arrives next day

24h 22m • 1 change
Arrives next day

22h 50m • 1 change
Arrives next day

21h 32m • 1 change
Arrives next day

22h 50m • 1 change
Want to know about travelling from 59th St. to New York Penn Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from 59th St. to New York Penn Station. However, there are services departing from 59th St. station and arriving at New York Penn Station station via New York Midtown. The journey, including transfers, takes approximately 21h 25m.
59th St. to New York Penn Station bus services, operated by Chicago Transit (CTA), depart from Chicago Bus Station.
59th St. to New York Penn Station bus services, operated by Chicago Transit (CTA), arrive at New York Midtown station.
The distance between 59th St. and New York Penn Station is 1,141 km. The road distance is 1,449 km.
Flixbus USA operates a bus from Chicago Bus Station to New York Midtown twice daily. Tickets cost $140–240 and the journey takes 17h 5m.