The average bus between Afyonkarahisar and Istanbul takes 8h 35m and the fastest bus takes 7h 45m. The bus service runs several times per day from Afyonkarahisar to Istanbul. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Afyonkarahisar and Istanbul. The earliest departure is at 2:00 AM at night, and the last departure from Afyonkarahisar is at 11:45 PM which arrives into Istanbul at 8:15 AM. All services require a transfer, and take on average 8h 35m. The schedules shown below are for the next available departures.

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8h 10m • 1 change

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7h 45m • 1 change

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8h 45m • 1 change

7h 45m • 1 change

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9h • 1 change

8h 45m • 1 change

7h 45m • 1 change

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8h 45m • 1 change

7h 45m • 1 change

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8h 45m • 1 change
Want to know about travelling from Afyonkarahisar to Istanbul? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Afyonkarahisar to Istanbul. However, there are services departing from Afyonkarahisar station and arriving at Istanbul station via İstanbul Dudullu bus station station. The journey, including transfers, takes approximately 8h 35m.
Afyonkarahisar to Istanbul bus services, operated by Kamil Koç, depart from Afyon bus station.
Afyonkarahisar to Istanbul bus services, operated by Kamil Koç, arrive at İstanbul Dudullu bus station.
Book your Afyonkarahisar to Istanbul bus tickets online with Kamil Koç.
The distance between Afyonkarahisar and Istanbul is 285.4 km. The road distance is 464 km.
Kamil Koç operates a bus from Afyon bus station to İstanbul Dudullu bus station every 3 hours. Tickets cost ₺600–900 and the journey takes 6h 25m.