The average bus between Ajijic and Mezcales takes 6h 8m and the fastest bus takes 5h 50m. There is a bus service every few hours from Ajijic to Mezcales. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Ajijic and Mezcales. The earliest departure is at 5:00 AM in the morning, and the last departure from Ajijic is at 6:30 PM which arrives into Mezcales at 12:50 AM. All services require a transfer at Central Vieja de Guadalajara and take an average of 6h 8m. The schedules shown below are for the next available departures.


5h 50m • 2 changes


5h 50m • 2 changes


5h 50m • 2 changes


5h 50m • 2 changes


5h 50m • 2 changes


5h 50m • 2 changes


5h 50m • 2 changes


5h 50m • 2 changes


5h 50m • 2 changes


5h 50m • 2 changes


5h 50m • 2 changes


5h 50m • 2 changes


5h 50m • 2 changes


5h 50m • 2 changes


5h 50m • 2 changes


5h 50m • 2 changes
Want to know about travelling from Ajijic to Mezcales? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Ajijic to Mezcales. However, there are services departing from Ajijic station and arriving at Mezcales station via Central Vieja de Guadalajara. The journey, including transfers, takes approximately 6h 8m.
Ajijic to Mezcales bus services, operated by Chapala Plus, depart from Ajijic station.
Ajijic to Mezcales bus services, operated by Chapala Plus, arrive at Mezcales station.
The distance between Ajijic and Mezcales is 215.8 km. The road distance is 336 km.
You can take a bus from Ajijic to Mezcales via Central Vieja de Guadalajara, Central de Autobuses Zapopan, and Terminal Zapopan in around 6h 23m.