The average bus between America Plaza Station and Otay Mesa takes 1h 42m and the fastest bus takes 1h 20m. There is an hourly bus service from America Plaza Station to Otay Mesa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between America Plaza Station and Otay Mesa. The earliest departure is at 5:54 AM in the morning, and the last departure from America Plaza Station is at 11:10 PM which arrives into Otay Mesa at 4:26 AM. All services require a transfer, and take on average 1h 42m. The schedules shown below are for the next available departures.

1h 37m • 1 change

1h 44m • 1 change

1h 35m • 1 change

1h 31m • 1 change

1h 24m • 1 change

1h 32m • 1 change

1h 21m • 1 change

1h 31m • 1 change

1h 24m • 1 change

1h 32m • 1 change

1h 21m • 1 change

1h 31m • 1 change
Want to know about travelling from America Plaza Station to Otay Mesa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from America Plaza Station to Otay Mesa. However, there are services departing from America Plaza Station station and arriving at Otay Mesa station via Otay Mesa Transit Center. The journey, including transfers, takes approximately 1h 42m.
America Plaza Station to Otay Mesa bus services, operated by San Diego Metro Transit, depart from Santa Fe Depot station.
America Plaza Station to Otay Mesa bus services, operated by San Diego Metro Transit, arrive at Otay Mesa Rd & Cactus Rd station.
The distance between America Plaza Station and Otay Mesa is 24.1 km. The road distance is 48 km.
You can take a bus from Santa Fe Depot to Otay Mesa Rd & Cactus Rd via Otay Mesa Transit Center in around 1h 37m.