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Amherst to Chicago buses

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Trip Overview

The average bus between Amherst and Chicago takes 13h 51m and the fastest bus takes 13h 30m. The bus service runs several times per day from Amherst to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

13h 51m
Duration
552 mi
Distance
$122
Average price
Twice daily
Frequency

Amherst to Chicago bus times

Buses run twice daily between Amherst and Chicago. The earliest departure is at 6:55 AM in the morning, and the last departure from Amherst is at 9:30 PM which arrives into Chicago at 10:00 AM. All services require a transfer at Wilkeson Way & LaRivere Drive and take an average of 13h 51m. The schedules shown below are for the next available departures.

Departing Wednesday, November 4, 2026

  •  → 

    NFTAGreyhound USAGreyhound USA14h 10m • 2 changes
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    Arrives next day

    NFTAGreyhound USAGreyhound USA13h 30m • 2 changes

Departing Thursday, November 5, 2026

  •  → 

    NFTAGreyhound USAGreyhound USA14h 10m • 2 changes
  •  → 

    Arrives next day

    NFTAGreyhound USAGreyhound USA13h 30m • 2 changes

Departing Friday, November 6, 2026

  •  → 

    NFTAGreyhound USAGreyhound USA14h 10m • 2 changes
  •  → 

    Arrives next day

    NFTAGreyhound USAGreyhound USA13h 30m • 2 changes

Departing Saturday, November 7, 2026

  •  → 

    NFTAGreyhound USAGreyhound USA14h 5m • 2 changes
  •  → 

    Arrives next day

    NFTAGreyhound USAGreyhound USA13h 45m • 2 changes

Departing Sunday, November 8, 2026

  •  → 

    NFTAGreyhound USAGreyhound USA14h 5m • 2 changes
  •  → 

    Arrives next day

    NFTAGreyhound USAGreyhound USA13h 45m • 2 changes

Departing Monday, November 9, 2026

  •  → 

    NFTAGreyhound USAGreyhound USA14h 10m • 2 changes
  •  → 

    Arrives next day

    NFTAGreyhound USAGreyhound USA13h 30m • 2 changes

Departing Tuesday, November 10, 2026

  •  → 

    NFTAGreyhound USAGreyhound USA14h 10m • 2 changes

Frequently asked questions

Want to know about travelling from Amherst to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Amherst to Chicago.ExpandLaunch map view
  • Distance: 552.5 mi
  • Duration: 13h 51m

What companies run services between Amherst, NY, USA and Chicago, IL, USA?

You can take a bus from Main Street & Jersey Left to Chicago Bus Station via Wilkeson Way & LaRivere Drive, Buffalo, and Cleveland Bus Station in around 13h 37m.

Operators