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Amsterdam to Mainz-Drais buses

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Trip Overview

The average bus between Amsterdam and Mainz-Drais takes 10h 44m and the fastest bus takes 7h 54m. The bus service runs several times per day from Amsterdam to Mainz-Drais. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

10h 44m
Duration
494 km
Distance
€51
Average price
3 times a day
Frequency

Amsterdam to Mainz-Drais bus times

Buses run 3 times a day between Amsterdam and Mainz-Drais. The earliest departure is at 9:50 AM in the morning, and the last departure from Amsterdam is at 11:45 PM which arrives into Mainz-Drais at 9:20 AM. All services require a transfer at Frankfurt central train station and take an average of 10h 44m. The schedules shown below are for the next available departures.

Departing Saturday, November 7, 2026

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    Arrives next day

    FlixBusFlixBusMainzer Mobilität8h 35m • 2 changes

Departing Sunday, November 8, 2026

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    FlixBusFlixBusMainzer Mobilität10h 21m • 2 changes
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    FlixBusFlixBusMainzer Mobilität12h 5m • 2 changes
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    Arrives next day

    FlixBusFlixBusMainzer Mobilität10h 9m • 2 changes
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    Arrives next day

    FlixBusFlixBusMainzer Mobilität10h 9m • 2 changes

Departing Monday, November 9, 2026

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    FlixBusFlixBusMainzer Mobilität10h 4m • 2 changes
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    FlixBusFlixBusMainzer Mobilität12h 35m • 2 changes
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    Arrives next day

    FlixBusFlixBusMainzer Mobilität10h 9m • 2 changes

Departing Tuesday, November 10, 2026

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    FlixBusFlixBusMainzer Mobilität13h 30m • 2 changes
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    Arrives next day

    FlixBusFlixBusMainzer Mobilität10h 9m • 2 changes

Departing Wednesday, November 11, 2026

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    FlixBusFlixBusMainzer Mobilität12h 51m • 2 changes
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    Arrives next day

    FlixBusFlixBusMainzer Mobilität7h 54m • 2 changes

Departing Thursday, November 12, 2026

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    FlixBusFlixBusMainzer Mobilität10h 4m • 2 changes
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    FlixBusFlixBusMainzer Mobilität12h 35m • 2 changes
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    Arrives next day

    FlixBusFlixBusMainzer Mobilität7h 54m • 2 changes

Departing Friday, November 13, 2026

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    FlixBusFlixBusMainzer Mobilität10h 4m • 2 changes
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    FlixBusFlixBusMainzer Mobilität11h 56m • 2 changes

Frequently asked questions

Want to know about travelling from Amsterdam to Mainz-Drais? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Amsterdam to Mainz-Drais.ExpandLaunch map view
  • Distance: 493.5 km
  • Duration: 10h 44m

What companies run services between Amsterdam, Netherlands and Mainz-Drais, Germany?

FlixBus operates a bus from Amsterdam Sloterdijk to Frankfurt central train station hourly. Tickets cost €40–60 and the journey takes 6h 5m.

Operators