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The average bus between Anaheim and Otay Mesa takes 4h 36m and the fastest bus takes 2h 54m. The bus service runs several times per day from Anaheim to Otay Mesa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Anaheim and Otay Mesa. The earliest departure is at 10:15 AM in the morning, and the last departure from Anaheim is at 9:40 PM which arrives into Otay Mesa at 5:03 AM. All services require a transfer at San Ysidro Transit Center and take an average of 4h 36m. The schedules shown below are for the next available departures.
Want to know about travelling from Anaheim to Otay Mesa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Anaheim to Otay Mesa. However, there are services departing from Anaheim Regional Transportation Intermodal Center station and arriving at San Ysidro Bus Terminal station via San Ysidro Bus Terminal station. The journey, including transfers, takes approximately 4h 36m.
Anaheim to Otay Mesa bus services, operated by Greyhound USA, depart from Anaheim Regional Transportation Intermodal Center station.
Anaheim to Otay Mesa bus services, operated by Greyhound USA, arrive at San Ysidro Bus Terminal station.
The distance between Anaheim and Otay Mesa is 165.7 km. The road distance is 179 km.
Greyhound USA operates a bus from Anaheim Regional Transportation Intermodal Center to San Ysidro Bus Terminal 3 times a day. Tickets cost $19–30 and the journey takes 2h 30m. Flixbus USA also services this route twice daily.
