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Ann Arbor to Florida Keys buses

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Trip Overview

The bus between Ann Arbor and Florida Keys takes 2d 6h. The bus runs, on average, 5 times per week from Ann Arbor to Florida Keys. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 6h
Duration
1,598 mi
Distance
$296
Average price
5 times a week
Frequency

Ann Arbor to Florida Keys bus times

Buses run 5 times a week between Ann Arbor and Florida Keys. The earliest departure is at 6:00 AM in the morning, and the last departure from Ann Arbor is at 6:00 AM which arrives into Florida Keys at 12:15 PM. All services require a transfer at Detroit Bus Station and take an average of 2d 6h. The schedules shown below are for the next available departures.

Departing Saturday, October 10, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USAGreyhound USAKey West Transit2d 6h • 4 changes

Departing Sunday, October 11, 2026

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    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USAGreyhound USAKey West Transit2d 6h • 4 changes

Departing Monday, October 12, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USAGreyhound USAKey West Transit2d 6h • 4 changes

Departing Tuesday, October 13, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USAGreyhound USAKey West Transit2d 6h • 4 changes

Departing Wednesday, October 14, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USAGreyhound USAKey West Transit2d 6h • 4 changes

Frequently asked questions

Want to know about travelling from Ann Arbor to Florida Keys? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Ann Arbor to Florida Keys.ExpandLaunch map view
  • Distance: 1,598.4 mi
  • Duration: 2d 6h

What companies run services between Ann Arbor, MI, USA and Florida Keys, FL, USA?

You can take a bus from Ann Arbor Amtrak Station to Florida Keys via Detroit Bus Station, Atlanta Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 38h 40m.

Operators