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Ann Arbor to Florida Keys buses

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Trip Overview

The average bus between Ann Arbor and Florida Keys takes 2d 16h and the fastest bus takes 2d 15h. The bus runs, on average, 5 times per week from Ann Arbor to Florida Keys. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 16h
Duration
1,600 mi
Distance
$341
Average price
5 times a week
Frequency

Ann Arbor to Florida Keys bus times

Buses run 5 times a week between Ann Arbor and Florida Keys. The earliest departure is at 8:15 PM in the evening, and the last departure from Ann Arbor is at 9:00 PM which arrives into Florida Keys at 12:15 PM. All services require a transfer at Detroit - Grand Circus Park and take an average of 2d 16h. The schedules shown below are for the next available departures.

Departing Friday, October 30, 2026

  •  → 

    Arrives +3 days

    D2A2DDotGreyhound USAGreyhound USAGreyhound USAKey West Transit2d 16h • 5 changes

Departing Saturday, October 31, 2026

  •  → 

    Arrives +3 days

    D2A2DDotGreyhound USAGreyhound USAGreyhound USAKey West Transit2d 17h • 5 changes

Departing Sunday, November 1, 2026

  •  → 

    Arrives +3 days

    D2A2DDotGreyhound USAGreyhound USAGreyhound USAKey West Transit2d 16h • 5 changes

Departing Monday, November 2, 2026

  •  → 

    Arrives +3 days

    D2A2DDotGreyhound USAGreyhound USAGreyhound USAKey West Transit2d 15h • 5 changes

Frequently asked questions

Want to know about travelling from Ann Arbor to Florida Keys? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Ann Arbor to Florida Keys.ExpandLaunch map view
  • Distance: 1,600.4 mi
  • Duration: 2d 16h

What companies run services between Ann Arbor, MI, USA and Florida Keys, FL, USA?

You can take a bus from Ann Arbor- Blake Transit Ctr., MI to Florida Keys via Detroit - Grand Circus Park, Rosa Parks Transit Center - Bay 10, Lafayette & Fifth, Detroit Bus Station, Atlanta Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 39h 15m.

Operators