Rome2Rio

Annapolis to South Carolina buses

Find Transport to South Carolina

View schedule

Trip Overview

The average bus between Annapolis and South Carolina takes 25h 35m and the fastest bus takes 22h 59m. The bus runs, on average, 6 times per week from Annapolis to South Carolina. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

25h 35m
Duration
621 mi
Distance
$135
Average price
6 times a week
Frequency

Annapolis to South Carolina bus times

Buses run 6 times a week between Annapolis and South Carolina. The service departs Annapolis at 5:00 PM in the evening, which arrives into South Carolina at 07:39:00. All services require a transfer at Washington Union Station and take an average of 25h 35m. The schedules shown below are for the next available departures.

Departing Saturday, November 7, 2026

  •  → 

    Arrives +2 days

    Flixbus USAGreyhound USAGreyhound USACARTACARTACARTA38h 39m • 5 changes

Departing Sunday, November 8, 2026

  •  → 

    Arrives next day

    Flixbus USAGreyhound USAGreyhound USACARTACARTACARTA22h 59m • 5 changes

Departing Monday, November 9, 2026

  •  → 

    Arrives next day

    Flixbus USAGreyhound USAGreyhound USACARTACARTACARTA22h 59m • 5 changes

Departing Tuesday, November 10, 2026

  •  → 

    Arrives next day

    Flixbus USAGreyhound USAGreyhound USACARTACARTACARTA22h 59m • 5 changes

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    Flixbus USAGreyhound USAGreyhound USACARTACARTACARTA22h 59m • 5 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    Flixbus USAGreyhound USAGreyhound USACARTACARTACARTA22h 59m • 5 changes

Frequently asked questions

Want to know about travelling from Annapolis to South Carolina? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Annapolis to South Carolina.ExpandLaunch map view
  • Distance: 621.3 mi
  • Duration: 25h 35m

What companies run services between Annapolis, MD, USA and South Carolina, USA?

You can take a bus from Annapolis to Broad St / Meeting St via Washington Union Station, Raleigh Bus Station, Charleston Bus Station, North Charleston Transit Center, N. Charleston SuperStop, Rivers Ave / Cosgrove Ave, Transit Mall, and Visitors Center on John St in around 16h 12m.

Operators