The average bus between Ascoli Piceno and Roma Termini takes 3h 48m and the fastest bus takes 3h 31m. The bus service runs several times per day from Ascoli Piceno to Roma Termini. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Ascoli Piceno and Roma Termini. The earliest departure is at 4:15 AM at night, and the last departure from Ascoli Piceno is at 5:35 PM which arrives into Roma Termini at 9:11 PM. All services require a transfer, and take on average 3h 48m. The schedules shown below are for the next available departures.

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3h 54m • 1 changeWant to know about travelling from Ascoli Piceno to Roma Termini? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Ascoli Piceno to Roma Termini. However, there are services departing from Ascoli Piceno station and arriving at Roma, Autostazione Tiburtina station via Roma, Autostazione Tiburtina station. The journey, including transfers, takes approximately 3h 48m.
Ascoli Piceno to Roma Termini bus services, operated by Start SPA, depart from Ascoli Piceno station.
Ascoli Piceno to Roma Termini bus services, operated by Start SPA, arrive at Roma, Autostazione Tiburtina station.
The distance between Ascoli Piceno and Roma Termini is 137.7 km. The road distance is 179 km.
Start SPA operates a bus from Ascoli Piceno to Roma, Autostazione Tiburtina every 4 hours. Tickets cost €7–15 and the journey takes 3h 10m. FlixBus also services this route once daily.