The average bus between Assisi (Station) and Rome takes 3h 24m and the fastest bus takes 3h 10m. The bus service runs several times per day from Assisi (Station) to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Assisi (Station) and Rome. The earliest departure is at 7:04 AM in the morning, and the last departure from Assisi (Station) is at 5:17 PM which arrives into Rome at 8:35 PM. All services require a transfer, and take on average 3h 24m. The schedules shown below are for the next available departures.

3h 10m • 1 change

3h 39m • 1 change

3h 20m • 1 change

3h 18m • 1 change

3h 10m • 1 change

3h 39m • 1 change

3h 20m • 1 change

3h 18m • 1 change

3h 10m • 1 change

3h 39m • 1 change

3h 20m • 1 change

3h 18m • 1 change
Want to know about travelling from Assisi (Station) to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Assisi (Station) to Rome. However, there are services departing from Assisi (Station) station and arriving at Rome station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 3h 24m.
Assisi (Station) to Rome bus services, operated by FlixBus, depart from Perugia station.
Assisi (Station) to Rome bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
Book your Assisi (Station) to Rome bus tickets online with FlixBus, Sulga Autolinee and Busitalia Umbria.
The distance between Assisi (Station) and Rome is 128.9 km. The road distance is 196 km.
FlixBus operates a bus from Perugia to Roma, Autostazione Tiburtina every 4 hours. Tickets cost €14–24 and the journey takes 2h 20m. Three other operators also service this route.