The average bus between Assisi Stazione and Rome takes 3h 24m and the fastest bus takes 3h 10m. The bus service runs several times per day from Assisi Stazione to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Assisi Stazione and Rome. The earliest departure is at 7:04 AM in the morning, and the last departure from Assisi Stazione is at 5:17 PM which arrives into Rome at 8:35 PM. All services require a transfer, and take on average 3h 24m. The schedules shown below are for the next available departures.

3h 10m • 1 change

3h 39m • 1 change

3h 20m • 1 change

3h 18m • 1 change

3h 26m • 1 change

3h 39m • 1 change

3h 20m • 1 change

3h 18m • 1 change
Want to know about travelling from Assisi Stazione to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Assisi Stazione to Rome. However, there are services departing from Assisi Stazione station and arriving at Rome station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 3h 24m.
Assisi Stazione to Rome bus services, operated by Busitalia Umbria, depart from Perugia station.
Assisi Stazione to Rome bus services, operated by Busitalia Umbria, arrive at Roma, Autostazione Tiburtina station.
Book your Assisi Stazione to Rome bus tickets online with Busitalia Umbria, Sulga Autolinee and FlixBus.
The distance between Assisi Stazione and Rome is 128.9 km. The road distance is 196 km.
FlixBus operates a bus from Perugia to Roma, Autostazione Tiburtina every 4 hours. Tickets cost €14–25 and the journey takes 2h 20m. Three other operators also service this route.