Avignon-Centre Station to Lyon Buses

Avignon-Centre Station to Lyon buses

Travel from

Search accommodation with Expedia

Trip Overview

The average bus between Avignon-Centre Station and Lyon takes 3h 35m and the fastest bus takes 2h 56m. The bus service runs several times per day from Avignon-Centre Station to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 35m
Duration: 239 km
Distance: €23
Average price: Every 4 hours
Frequency

Bus

best

Take the bus from Avignon - Le Pontet - Le Lac Stop to Lyon - Gerland Bus Stationbus BlaBlaCar Bus

3h 48m

€15–29

Avignon-Centre Station to Lyon bus times

Buses run every 4 hours between Avignon-Centre Station and Lyon. The earliest departure is at 12:00 AM at night, and the last departure from Avignon-Centre Station is at 11:42 PM which arrives into Lyon at 12:55 AM. All services require a transfer at Le Lac and take an average of 3h 35m. The schedules shown below are for the next available departures.

Departing Tuesday, October 13, 2026

6:31 PM → 9:45 PM
3h 14m • 1 change
9:53 PM → 12:50 AM
Arrives next day
2h 57m • 1 change
10:30 PM → 3:10 AM
Arrives next day
4h 40m • 1 change

Departing Wednesday, October 14, 2026

7:57 AM → 11:50 AM
3h 53m • 1 change
6:31 PM → 9:45 PM
3h 14m • 1 change
9:53 PM → 12:50 AM
Arrives next day
2h 57m • 1 change
10:30 PM → 12:55 AM
Arrives next day
4h 25m • 1 change

Departing Thursday, October 15, 2026

7:57 AM → 11:50 AM
3h 53m • 1 change
6:31 PM → 9:45 PM
3h 14m • 1 change
9:53 PM → 12:50 AM
Arrives next day
2h 57m • 1 change
10:30 PM → 12:55 AM
Arrives next day
4h 25m • 1 change

Departing Friday, October 16, 2026

7:57 AM → 11:50 AM
3h 53m • 1 change
9:53 AM → 1:15 PM
3h 22m • 1 change
11:20 AM → 3:05 PM
3h 45m • 1 change
12:32 PM → 4:05 PM
3h 33m • 1 change
Show more

Departing Saturday, October 17, 2026

12:00 AM → 3:10 AM
3h 10m • 1 change
8:00 AM → 11:50 AM
3h 50m • 1 change
9:39 AM → 1:15 PM
3h 36m • 1 change
11:24 AM → 3:05 PM
3h 41m • 1 change
Show more

Departing Sunday, October 18, 2026

12:00 AM → 3:10 AM
3h 10m • 1 change
7:50 AM → 11:50 AM
4h • 1 change
9:28 AM → 1:15 PM
3h 47m • 1 change
11:14 AM → 3:05 PM
3h 51m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Avignon-Centre Station to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Avignon-Centre Station to Lyon buses

Trip Overview

Bus