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Avignon Centre to Lyon buses

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Trip Overview

The average bus between Avignon Centre and Lyon takes 3h 36m and the fastest bus takes 2h 56m. The bus service runs several times per day from Avignon Centre to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 36m
Duration
239 km
Distance
€24
Average price
Every 4 hours
Frequency

Avignon Centre to Lyon bus times

Buses run every 4 hours between Avignon Centre and Lyon. The earliest departure is at 12:00 AM at night, and the last departure from Avignon Centre is at 11:42 PM which arrives into Lyon at 1:55 AM. All services require a transfer at Le Lac and take an average of 3h 36m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

  •  → 

    TecelysFlixBus3h 14m • 1 change
  •  → 

    Arrives next day

    TecelysBlaBlaCar Bus2h 57m • 1 change
  •  → 

    Arrives next day

    TecelysBlaBlaCar Bus4h 40m • 1 change

Departing Wednesday, November 11, 2026

  •  → 

    TecelysBlaBlaCar Bus4h • 1 change
  •  → 

    TecelysFlixBus3h 47m • 1 change
  •  → 

    TecelysFlixBus3h 51m • 1 change
  •  → 

    TecelysFlixBus3h 35m • 1 change
  • Show more

Departing Thursday, November 12, 2026

  •  → 

    TecelysBlaBlaCar Bus3h 53m • 1 change
  •  → 

    TecelysFlixBus3h 22m • 1 change
  •  → 

    TecelysFlixBus3h 45m • 1 change
  •  → 

    TecelysFlixBus3h 40m • 1 change
  • Show more

Departing Friday, November 13, 2026

  •  → 

    TecelysBlaBlaCar Bus3h 53m • 1 change
  •  → 

    TecelysFlixBus3h 22m • 1 change
  •  → 

    TecelysFlixBus3h 45m • 1 change
  •  → 

    TecelysFlixBus3h 40m • 1 change
  • Show more

Departing Saturday, November 14, 2026

  •  → 

    TecelysBlaBlaCar Bus3h 10m • 1 change
  •  → 

    TecelysBlaBlaCar Bus3h 50m • 1 change
  •  → 

    TecelysFlixBus3h 36m • 1 change
  •  → 

    TecelysFlixBus3h 41m • 1 change
  • Show more

Departing Sunday, November 15, 2026

  •  → 

    TecelysBlaBlaCar Bus3h 10m • 1 change
  •  → 

    TecelysBlaBlaCar Bus4h • 1 change
  •  → 

    TecelysFlixBus3h 47m • 1 change
  •  → 

    TecelysFlixBus3h 51m • 1 change
  • Show more

Departing Monday, November 16, 2026

  •  → 

    TecelysBlaBlaCar Bus3h 53m • 1 change
  •  → 

    TecelysFlixBus3h 22m • 1 change
  •  → 

    TecelysFlixBus3h 45m • 1 change
  •  → 

    TecelysFlixBus3h 40m • 1 change
  • Show more

Frequently asked questions

Want to know about travelling from Avignon Centre to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Avignon Centre to Lyon.ExpandLaunch map view
  • Distance: 239.4 km
  • Duration: 3h 36m

What companies run services between Avignon Centre, France and Lyon, France?

FlixBus operates a bus from Avignon to Lyon 5 times a day. Tickets cost €19–29 and the journey takes 2h 40m. BlaBlaCar Bus also services this route every 4 hours.

Operators