The average bus between Aylesbury and Southampton takes 4h 46m and the fastest bus takes 4h. There is a bus service every few hours from Aylesbury to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Aylesbury and Southampton. The earliest departure is at 5:10 AM in the morning, and the last departure from Aylesbury is at 11:00 PM which arrives into Southampton at 8:55 AM. All services require a transfer at High Wycombe BusStn and take an average of 4h 46m. The schedules shown below are for the next available departures.


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4h 20m • 2 changesWant to know about travelling from Aylesbury to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Aylesbury to Southampton. However, there are services departing from Aylesbury station and arriving at Southampton station via High Wycombe BusStn. The journey, including transfers, takes approximately 4h 46m.
Aylesbury to Southampton bus services, operated by Redline, depart from Aylesbury Bus Stn station.
Aylesbury to Southampton bus services, operated by Redline, arrive at Coach Station.
The distance between Aylesbury and Southampton is 109.4 km. The road distance is 174 km.
You can take a bus from Aylesbury Bus Stn to Coach Station via High Wycombe BusStn and Heathrow Central Bus Station in around 4h 40m.