Aylesbury to Southampton Buses

Aylesbury to Southampton buses

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Trip Overview

The average bus between Aylesbury and Southampton takes 5h and the fastest bus takes 4h. The bus service runs several times per day from Aylesbury to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h
Duration: 108 mi
Distance: Every 4 hours
Frequency

Line 300 bus, line 102 bus, bus

best

Take the bus from Aylesbury Bus Stn to High Wycombe BusStnbus 300 / ...
Take the bus from High Wycombe BusStn to Heathrow Central Bus Stationbus 102
Take the bus from Heathrow Central Bus Station to Coach Stationbus 032 / ...

4h 50m

Aylesbury to Southampton bus times

Buses run every 4 hours between Aylesbury and Southampton. The earliest departure is at 5:10 AM in the morning, and the last departure from Aylesbury is at 11:00 PM which arrives into Southampton at 8:55 AM. All services require a transfer at High Wycombe BusStn and take an average of 5h. The schedules shown below are for the next available departures.

Departing Thursday, October 22, 2026

5:10 AM → 9:10 AM
4h • 2 changes
6:40 AM → 11:20 AM
4h 40m • 2 changes
8:25 AM → 1:00 PM
4h 35m • 2 changes
9:55 AM → 2:20 PM
4h 25m • 2 changes
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Departing Friday, October 23, 2026

5:10 AM → 9:10 AM
4h • 2 changes
6:00 AM → 10:50 AM
4h 50m • 2 changes
7:45 AM → 12:20 PM
4h 35m • 2 changes
9:25 AM → 1:45 PM
4h 20m • 2 changes
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Departing Saturday, October 24, 2026

5:25 AM → 10:50 AM
5h 25m • 2 changes
7:25 AM → 12:20 PM
4h 55m • 2 changes
9:05 AM → 1:30 PM
4h 25m • 2 changes
9:40 AM → 2:20 PM
4h 40m • 2 changes
Show more

Frequently asked questions

Want to know about travelling from Aylesbury to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.