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Baltimore to Florida Keys buses

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Trip Overview

The average bus between Baltimore and Florida Keys takes 40h 15m and the fastest bus takes 39h 45m. The bus runs, on average, 4 times per week from Baltimore to Florida Keys. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

40h 15m
Duration
1,279 mi
Distance
$250
Average price
4 times a week
Frequency

Baltimore to Florida Keys bus times

Buses run 4 times a week between Baltimore and Florida Keys. The service departs Baltimore at 8:30 PM in the evening, which arrives into Florida Keys at 12:15:00. All services require a transfer at Orlando Bus Station and take an average of 40h 15m. The schedules shown below are for the next available departures.

Departing Saturday, October 31, 2026

  •  → 

    Arrives +2 days

    Flixbus USAFlixbus USAGreyhound USAKey West Transit40h 45m • 3 changes

Departing Sunday, November 1, 2026

  •  → 

    Arrives +2 days

    Flixbus USAFlixbus USAGreyhound USAKey West Transit39h 45m • 3 changes

Departing Wednesday, November 4, 2026

  •  → 

    Arrives +2 days

    Flixbus USAFlixbus USAGreyhound USAKey West Transit39h 45m • 3 changes

Frequently asked questions

Want to know about travelling from Baltimore to Florida Keys? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Baltimore to Florida Keys.ExpandLaunch map view
  • Distance: 1,278.6 mi
  • Duration: 40h 15m

What companies run services between Baltimore, MD, USA and Florida Keys, FL, USA?

You can take a bus from Baltimore Downtown Bus Station to Florida Keys via Orlando Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 29h 30m.

Operators