The average bus between Baltimore and Orangeburg takes 5h 56m and the fastest bus takes 5h. The bus service runs several times per day from Baltimore to Orangeburg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Baltimore and Orangeburg. The earliest departure is at 9:00 AM in the morning, and the last departure from Baltimore is at 2:00 PM which arrives into Orangeburg at 7:00 PM. All services require a transfer, and take on average 5h 56m. The schedules shown below are for the next available departures.

6h 30m • 1 change

6h 50m • 1 change

5h 25m • 1 change

5h • 1 change

6h 30m • 1 change

6h 50m • 1 change

5h 25m • 1 change

5h • 1 change
Want to know about travelling from Baltimore to Orangeburg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Baltimore to Orangeburg. However, there are services departing from Baltimore station and arriving at Orangeburg station via Port Authority Bus Terminal. The journey, including transfers, takes approximately 5h 56m.
Baltimore to Orangeburg bus services, operated by Peter Pan Bus Lines, depart from Baltimore Downtown Bus Station.
Baltimore to Orangeburg bus services, operated by Peter Pan Bus Lines, arrive at Western Hwy & Orangeburg Rd station.
The distance between Baltimore and Orangeburg is 298.8 km. The road distance is 481 km.
You can take a bus from Baltimore Downtown Bus Station to Western Hwy & Orangeburg Rd via Port Authority Bus Terminal in around 5h 35m.