The average bus between Baltimore and Southampton takes 5h and the fastest bus takes 4h 6m. The bus service runs several times per day from Baltimore to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Baltimore and Southampton. The earliest departure is at 2:30 AM at night, and the last departure from Baltimore is at 5:40 PM which arrives into Southampton at 10:43 PM. All services require a transfer at Philadelphia and take an average of 5h. The schedules shown below are for the next available departures.


5h 39m • 2 changes


5h 39m • 2 changes


5h 39m • 2 changes


5h 39m • 2 changes


5h 39m • 2 changes
Want to know about travelling from Baltimore to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Baltimore to Southampton. However, there are services departing from Baltimore station and arriving at Southampton station via Philadelphia. The journey, including transfers, takes approximately 5h.
Baltimore to Southampton bus services, operated by Greyhound-us, depart from Baltimore station.
Baltimore to Southampton bus services, operated by Greyhound-us, arrive at 2nd St Pk & Hampton Av - FS station.
The distance between Baltimore and Southampton is 166.3 km. The road distance is 201 km.
You can take a bus from Baltimore to 2nd St Pk & Hampton Av - FS via Philadelphia, Spring Garden, Frankford Transit Center, and Frankford Transit Center - Rt 24 in around 4h 49m.