The average bus between Berlin and Prague 2 takes 5h 6m and the fastest bus takes 4h 35m. There is a bus service every few hours from Berlin to Prague 2. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Berlin and Prague 2. The earliest departure is at 2:25 AM at night, and the last departure from Berlin is at 11:59 PM which arrives into Prague 2 at 5:14 AM. All services require a transfer at Praha, ÚAN Florenc and take an average of 5h 6m. The schedules shown below are for the next available departures.

5h 7m • 1 change

4h 47m • 1 change

4h 58m • 1 change

4h 44m • 1 change

5h 52m • 1 change

5h 57m • 1 change

5h 7m • 1 change

4h 47m • 1 change

5h 52m • 1 change

5h 57m • 1 change

5h 7m • 1 change

4h 47m • 1 change

5h 52m • 1 change

5h 57m • 1 change

5h 7m • 1 change

4h 47m • 1 change
Want to know about travelling from Berlin to Prague 2? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Berlin to Prague 2. However, there are services departing from Berlin station and arriving at Prague 2 station via Praha, ÚAN Florenc. The journey, including transfers, takes approximately 5h 6m.
Berlin to Prague 2 bus services, operated by FlixBus, depart from Berlin, Zentralen Omnibusbahnhof station.
Berlin to Prague 2 bus services, operated by FlixBus, arrive at Praha, ÚAN Florenc station.
Book your Berlin to Prague 2 bus tickets online with FlixBus and Pražská integrovaná doprava.
The distance between Berlin and Prague 2 is 281.7 km. The road distance is 342 km.
FlixBus operates a bus from Berlin, Zentralen Omnibusbahnhof to Praha, ÚAN Florenc hourly. Tickets cost Kč 650–1,200 and the journey takes 4h 20m.