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Big Pine Key to Key West (Island) buses

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Trip Overview

The average bus between Big Pine Key and Key West (Island) takes 47 min and the fastest bus takes 45 min. There is a bus service every few hours from Big Pine Key to Key West (Island). The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

47 min
Duration
28 mi
Distance
$6
Average price
Every 2 hours
Frequency

Big Pine Key to Key West (Island) bus times

Buses run every 2 hours between Big Pine Key and Key West (Island). The earliest departure is at 6:13 AM in the morning, and the last departure from Big Pine Key is at 8:54 PM which arrives into Key West (Island) at 9:40 PM. All services run direct with no transfers required, and take on average 47 min. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

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    bus bus 47 min • Direct
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    bus bus 45 min • Direct
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    bus bus 47 min • Direct
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    bus bus 47 min • Direct
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Departing Friday, November 13, 2026

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    bus bus 47 min • Direct
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    bus bus 47 min • Direct
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    bus bus 45 min • Direct
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    bus bus 45 min • Direct
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Departing Saturday, November 14, 2026

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    bus bus 47 min • Direct
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    bus bus 47 min • Direct
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    bus bus 45 min • Direct
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    bus bus 45 min • Direct
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Departing Sunday, November 15, 2026

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    bus bus 47 min • Direct
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    bus bus 47 min • Direct
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    bus bus 45 min • Direct
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    bus bus 45 min • Direct
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Departing Monday, November 16, 2026

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    bus bus 47 min • Direct
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    bus bus 47 min • Direct
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    bus bus 45 min • Direct
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    bus bus 45 min • Direct
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Departing Tuesday, November 17, 2026

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    bus bus 47 min • Direct
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    bus bus 47 min • Direct
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    bus bus 45 min • Direct
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    bus bus 45 min • Direct
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Departing Wednesday, November 18, 2026

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    bus bus 47 min • Direct
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    bus bus 47 min • Direct
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    bus bus 45 min • Direct
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    bus bus 47 min • Direct
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Frequently asked questions

Want to know about travelling from Big Pine Key to Key West (Island)? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Big Pine Key to Key West (Island).ExpandLaunch map view
  • Distance: 27.5 mi
  • Duration: 47 min

What companies run services between Big Pine Key, FL, USA and Key West (Island), FL, USA?

Key West Transit operates a bus from Big Pine Key - Medical Center to College Road Prior to Botanical Garden every 3 hours. Tickets cost $2–4 and the journey takes 47 min. Greyhound USA also services this route 3 times a day.

Operators