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Boston Airport (BOS) to St. Louis buses

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Trip Overview

The average bus between Boston Airport (BOS) and St. Louis takes 32h 40m and the fastest bus takes 31h 12m. There is at least one bus per day from Boston Airport (BOS) to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

32h 40m
Duration
1,254 mi
Distance
$269
Average price
Once daily
Frequency

Boston Airport (BOS) to St. Louis bus times

Buses run once daily between Boston Airport (BOS) and St. Louis. The earliest departure is at 2:30 PM in the afternoon, and the last departure from Boston Airport (BOS) is at 4:38 PM which arrives into St. Louis at 10:50 PM. All services require a transfer at South Station and take an average of 32h 40m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

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    Arrives next day

    MBTAFlixbus USAGreyhound USA31h 16m • 2 changes

Departing Monday, November 9, 2026

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    Arrives next day

    MBTAFlixbus USAGreyhound USA31h 12m • 2 changes

Departing Tuesday, November 10, 2026

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    Arrives next day

    MBTAGreyhound USAGreyhound USA33h 20m • 2 changes

Departing Wednesday, November 11, 2026

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    Arrives next day

    MBTAGreyhound USAGreyhound USA33h 20m • 2 changes

Departing Thursday, November 12, 2026

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    Arrives next day

    MBTAGreyhound USAGreyhound USA33h 20m • 2 changes

Departing Friday, November 13, 2026

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    Arrives next day

    MBTAFlixbus USAGreyhound USA31h 12m • 2 changes

Frequently asked questions

Want to know about travelling from Boston Airport (BOS) to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Boston Airport (BOS) to St. Louis.ExpandLaunch map view
  • Distance: 1,253.9 mi
  • Duration: 32h 40m

What companies run services between Boston Airport (BOS), USA and St. Louis, MO, USA?

You can take a bus from Terminal C - Arrivals Level to St Louis Bus Station via South Station, Boston, and Newark Penn Station in around 29h 26m.

Operators