The average bus between Boston and Mark Twain House Museum takes 2h 37m and the fastest bus takes 1h 54m. There is a bus service every few hours from Boston to Mark Twain House Museum. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Boston and Mark Twain House Museum. The earliest departure is at 2:15 AM at night, and the last departure from Boston is at 9:30 PM which arrives into Mark Twain House Museum at 11:52 PM. All services require a transfer at Hartford, Union Station and take an average of 2h 37m. The schedules shown below are for the next available departures.

2h 19m • 1 change

1h 58m • 1 change

1h 54m • 1 change

2h 8m • 1 change

2h 50m • 1 change

2h 19m • 1 change

1h 58m • 1 change

1h 54m • 1 change

4h 6m • 1 change

2h 26m • 1 change

2h 6m • 1 change

2h 2m • 1 change

4h 41m • 1 change

2h 31m • 1 change

2h 21m • 1 change

2h 7m • 1 change
Want to know about travelling from Boston to Mark Twain House Museum? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Boston to Mark Twain House Museum. However, there are services departing from Boston station and arriving at Mark Twain House Museum station via Hartford Union Station station. The journey, including transfers, takes approximately 2h 37m.
Boston to Mark Twain House Museum bus services, operated by Greyhound USA, depart from Boston station.
Boston to Mark Twain House Museum bus services, operated by Greyhound USA, arrive at Hartford Union Station.
Book your Boston to Mark Twain House Museum bus tickets online with Greyhound USA, CT Transit and Flixbus USA.
The distance between Boston and Mark Twain House Museum is 150.4 km. The road distance is 163 km.
Greyhound USA operates a bus from Boston to Hartford Union Station hourly. Tickets cost $15–30 and the journey takes 1h 50m. Two other operators also service this route.