The average bus between Boston and Melrose takes 4h 57m and the fastest bus takes 4h 29m. The bus service runs several times per day from Boston to Melrose. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Boston and Melrose. The earliest departure is at 1:30 AM at night, and the last departure from Boston is at 3:05 PM which arrives into Melrose at 8:05 PM. All services require a transfer at New York Midtown and take an average of 4h 57m. The schedules shown below are for the next available departures.

4h 47m • 1 change

4h 54m • 1 change

5h 44m • 1 change

5h • 1 change

4h 57m • 1 change

4h 45m • 1 change

4h 50m • 1 change

5h 41m • 1 change

4h 31m • 1 change

4h 52m • 1 change

4h 53m • 1 change

5h 45m • 1 change

4h 29m • 1 change

4h 30m • 1 change

4h 47m • 1 change

4h 54m • 1 change

4h 29m • 1 change

4h 47m • 1 change

4h 54m • 1 change

5h 44m • 1 change

4h 29m • 1 change

4h 47m • 1 change

4h 54m • 1 change

5h 44m • 1 change

4h 29m • 1 change

4h 47m • 1 change

4h 54m • 1 change

5h 44m • 1 change
Want to know about travelling from Boston to Melrose? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Boston to Melrose. However, there are services departing from Boston station and arriving at Melrose station via New York Midtown. The journey, including transfers, takes approximately 4h 57m.
Boston to Melrose bus services, operated by Greyhound USA, depart from Boston station.
Boston to Melrose bus services, operated by Greyhound USA, arrive at New York Midtown station.
The distance between Boston and Melrose is 292 km. The road distance is 355 km.
Flixbus USA operates a bus from Boston to New York Midtown hourly. Tickets cost $30–60 and the journey takes 4h 20m.