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Brandon to Key Largo buses

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Trip Overview

The average bus between Brandon and Key Largo takes 15h 50m and the fastest bus takes 11h 21m. The bus service runs several times per day from Brandon to Key Largo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

15h 50m
Duration
357 mi
Distance
$76
Average price
Twice daily
Frequency

Brandon to Key Largo bus times

Buses run twice daily between Brandon and Key Largo. The earliest departure is at 12:27 PM in the afternoon, and the last departure from Brandon is at 10:25 PM which arrives into Key Largo at 6:25 AM. All services require a transfer at Tampa Bus Station and take an average of 15h 50m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    Arrives next day

    Hillsborough Area Regional TransitGreyhound USAGreyhound USA17h 57m • 2 changes
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    Arrives next day

    Hillsborough Area Regional TransitFlixbus USAGreyhound USA14h 21m • 2 changes

Departing Thursday, November 12, 2026

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    Arrives next day

    Hillsborough Area Regional TransitFlixbus USAGreyhound USA15h 59m • 2 changes
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    Arrives next day

    Hillsborough Area Regional TransitFlixbus USAGreyhound USA11h 21m • 2 changes

Departing Friday, November 13, 2026

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    Arrives next day

    Hillsborough Area Regional TransitFlixbus USAGreyhound USA15h 59m • 2 changes
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    Arrives next day

    Hillsborough Area Regional TransitFlixbus USAGreyhound USA11h 21m • 2 changes

Departing Saturday, November 14, 2026

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    Arrives next day

    Hillsborough Area Regional TransitFlixbus USAGreyhound USA16h 3m • 2 changes
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    Arrives next day

    Hillsborough Area Regional TransitFlixbus USAGreyhound USA11h 54m • 2 changes
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    Arrives +2 days

    Hillsborough Area Regional TransitFlixbus USAGreyhound USA31h 59m • 2 changes

Departing Monday, November 16, 2026

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    Arrives next day

    Hillsborough Area Regional TransitFlixbus USAGreyhound USA15h 59m • 2 changes
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    Arrives next day

    Hillsborough Area Regional TransitFlixbus USAGreyhound USA11h 21m • 2 changes

Frequently asked questions

Want to know about travelling from Brandon to Key Largo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Brandon to Key Largo.ExpandLaunch map view
  • Distance: 357.2 mi
  • Duration: 15h 50m

What companies run services between Brandon, FL, USA and Key Largo, FL, USA?

You can take a bus from Town Center Blvd @ Providence Rd to Key Largo Bus Stop via Tampa Bus Station and Miami Airport Station in around 9h 46m.

Operators