The average bus between Brest and Prague takes 25h 28m and the fastest bus takes 24h 10m. There is at least one bus per day from Brest to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Brest and Prague. The earliest departure is at 10:25 AM in the morning, and the last departure from Brest is at 8:50 PM which arrives into Prague at 11:10 PM. All services require a transfer, and take on average 25h 28m. The schedules shown below are for the next available departures.
Arrives next day

24h 10m • 1 changeArrives next day

26h 20m • 1 changeArrives next day

24h 10m • 1 changeArrives next day

26h 20m • 1 changeWant to know about travelling from Brest to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Brest to Prague. However, there are services departing from Brest station and arriving at Prague station via Paris, Quai de Bercy (Bercy Seine). The journey, including transfers, takes approximately 25h 28m.
Brest to Prague bus services, operated by FlixBus, depart from Brest station.
Brest to Prague bus services, operated by FlixBus, arrive at Praha, ÚAN Florenc station.
Book your Brest to Prague bus tickets online with FlixBus.
The distance between Brest and Prague is 1,381.8 km. The road distance is 1,696 km.
You can take a bus from Brest to Praha, ÚAN Florenc via Paris, Quai de Bercy (Bercy Seine) in around 23h 40m.