The average bus between Brest and Prague takes 23h 49m and the fastest bus takes 21h 40m. The bus service runs several times per day from Brest to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Brest and Prague. The earliest departure is at 12:55 PM in the afternoon, and the last departure from Brest is at 8:50 PM which arrives into Prague at 11:10 PM. All services require a transfer, and take on average 23h 49m. The schedules shown below are for the next available departures.
Arrives next day

21h 40m • 1 change
Arrives next day

26h 20m • 1 change
Arrives next day

21h 40m • 1 change
Arrives next day

26h 20m • 1 change
Arrives next day

21h 40m • 1 change
Arrives next day

26h 20m • 1 change
Arrives next day

21h 40m • 1 change
Arrives next day

26h 20m • 1 change
Want to know about travelling from Brest to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Brest to Prague. However, there are services departing from Brest station and arriving at Prague station via Paris, Quai de Bercy (Bercy Seine). The journey, including transfers, takes approximately 23h 49m.
Brest to Prague bus services, operated by FlixBus, depart from Brest station.
Brest to Prague bus services, operated by FlixBus, arrive at Praha, ÚAN Florenc station.
Book your Brest to Prague bus tickets online with FlixBus.
The distance between Brest and Prague is 1,381.8 km. The road distance is 1,621 km.
You can take a bus from Brest to Praha, ÚAN Florenc via Paris, Quai de Bercy (Bercy Seine) in around 22h.