The average bus between Brindisi and Cassino takes 9h 4m and the fastest bus takes 7h. The bus service runs several times per day from Brindisi to Cassino. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Brindisi and Cassino. The earliest departure is at 7:20 AM in the morning, and the last departure from Brindisi is at 9:30 PM which arrives into Cassino at 8:59 AM. All services require a transfer, and take on average 9h 4m. The schedules shown below are for the next available departures.

9h 5m • 1 change

7h • 1 change
Arrives next day

11h 29m • 1 change

9h 5m • 1 change

7h • 1 change
Arrives next day

11h 29m • 1 change

9h 5m • 1 change

7h • 1 change
Arrives next day

11h 29m • 1 change

9h 5m • 1 change

7h • 1 change
Arrives next day

11h 29m • 1 change

9h 5m • 1 change

7h • 1 change
Arrives next day

11h 29m • 1 change
Want to know about travelling from Brindisi to Cassino? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Brindisi to Cassino. However, there are services departing from Brindisi station and arriving at Cassino station via Napoli P.zza Garibaldi. The journey, including transfers, takes approximately 9h 4m.
Brindisi to Cassino bus services, operated by FlixBus, depart from Brindisi station.
Brindisi to Cassino bus services, operated by FlixBus, arrive at Cassino station.
Book your Brindisi to Cassino bus tickets online with FlixBus.
The distance between Brindisi and Cassino is 357.2 km. The road distance is 467 km.
You can take a bus from Brindisi to Cassino via Napoli P.zza Garibaldi in around 7h 5m.