The bus between Brindisi and Isernia takes 5h 29m. There is at least one bus per day from Brindisi to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Brindisi and Isernia. The earliest departure is at 6:05 AM in the morning, and the last departure from Brindisi is at 6:05 AM which arrives into Isernia at 11:34 AM. All services require a transfer, and take on average 5h 29m. The schedules shown below are for the next available departures.
Want to know about travelling from Brindisi to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Brindisi to Isernia. However, there are services departing from Brindisi station and arriving at Isernia station via Foggia. The journey, including transfers, takes approximately 5h 29m.
Brindisi to Isernia bus services, operated by FlixBus, depart from Brindisi station.
Brindisi to Isernia bus services, operated by FlixBus, arrive at Isernia station.
Book your Brindisi to Isernia bus tickets online with FlixBus.
The distance between Brindisi and Isernia is 328.1 km. The road distance is 422 km.
You can take a bus from Brindisi to Isernia via Foggia in around 7h 9m.
