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Brindisi to San Sebastián de los Reyes buses

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Trip Overview

The bus between Brindisi and San Sebastián de los Reyes takes 2d 12h. The bus runs, on average, 2 times per week from Brindisi to San Sebastián de los Reyes. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 12h
Duration
2,728 km
Distance
€271
Average price
Twice a week
Frequency

Brindisi to San Sebastián de los Reyes bus times

Buses run twice a week between Brindisi and San Sebastián de los Reyes. The service departs Brindisi at 5:15 PM in the evening, which arrives into San Sebastián de los Reyes at 06:20:00. All services require a transfer at Milan and take an average of 2d 12h. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

  •  → 

    Arrives +3 days

    FlixBusFlixBusEmpresa Municipal de TransportesEmpresa Municipal de TransportesConsorcio de Transportes de Madrid2d 12h • 4 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives +3 days

    FlixBusFlixBusEmpresa Municipal de TransportesEmpresa Municipal de TransportesConsorcio de Transportes de Madrid2d 12h • 4 changes

Frequently asked questions

Want to know about travelling from Brindisi to San Sebastián de los Reyes? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Brindisi to San Sebastián de los Reyes.ExpandLaunch map view
  • Distance: 2,728.4 km
  • Duration: 2d 12h

What companies run services between Brindisi, Italy and San Sebastián de los Reyes, Spain?

You can take a bus from Brindisi Istituto Professionale Falcone to Pºeuropa-Av.Montes De Oca via Milan, Madrid, Méndez Álvaro, Cuatro Caminos, Avenida De Asturias - Plaza De Castilla, and Intercambiador De Plaza Castilla in around 39h 55m.

Operators