The average bus between Brindisi and Vatican Museums takes 8h 30m and the fastest bus takes 8h 2m. The bus service runs several times per day from Brindisi to Vatican Museums. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Brindisi and Vatican Museums. The earliest departure is at 9:55 AM in the morning, and the last departure from Brindisi is at 11:30 PM which arrives into Vatican Museums at 7:35 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 8h 30m. The schedules shown below are for the next available departures.

9h 23m • 1 change
8h 43m • 1 changeArrives next day

8h 24m • 1 changeArrives next day

8h 8m • 1 change
8h 11m • 1 change
9h 6m • 1 change
8h 38m • 1 changeArrives next day

8h 24m • 1 change
8h 11m • 1 change
9h 6m • 1 change
8h 38m • 1 changeArrives next day

8h 24m • 1 change
8h 11m • 1 change
9h 6m • 1 change
8h 38m • 1 changeArrives next day

8h 24m • 1 change
8h 11m • 1 change
9h 6m • 1 change
8h 38m • 1 changeArrives next day

8h 24m • 1 change
8h 11m • 1 change
9h 6m • 1 change
8h 38m • 1 changeArrives next day

8h 25m • 1 changeWant to know about travelling from Brindisi to Vatican Museums? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Brindisi to Vatican Museums. However, there are services departing from Brindisi station and arriving at Vatican Museums station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 8h 30m.
Brindisi to Vatican Museums bus services, operated by FlixBus, depart from Brindisi station.
Brindisi to Vatican Museums bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
The distance between Brindisi and Vatican Museums is 479.4 km. The road distance is 547 km.
FlixBus operates a bus from Brindisi to Roma, Autostazione Tiburtina 5 times a day. Tickets cost €40–70 and the journey takes 7h 25m.