The average bus between Brno and Nové Mesto takes 2h 31m and the fastest bus takes 2h 4m. The bus service runs several times per day from Brno to Nové Mesto. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Brno and Nové Mesto. The earliest departure is at 4:05 AM at night, and the last departure from Brno is at 11:59 PM which arrives into Nové Mesto at 5:19 AM. All services require a transfer, and take on average 2h 31m. The schedules shown below are for the next available departures.

2h 14m • 1 change

2h 4m • 1 change

2h 24m • 1 change
Arrives next day

5h 20m • 1 change

2h 4m • 1 change

2h 4m • 1 change

2h 29m • 1 change

2h 4m • 1 change

2h 4m • 1 change

2h 4m • 1 change

2h 29m • 1 change

2h 4m • 1 change

2h 4m • 1 change

2h 4m • 1 change

2h 29m • 1 change

2h 4m • 1 change

2h 4m • 1 change

2h 4m • 1 change

2h 29m • 1 change

2h 4m • 1 change

2h 4m • 1 change

2h 4m • 1 change

2h 29m • 1 change

2h 4m • 1 change
Want to know about travelling from Brno to Nové Mesto? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Brno to Nové Mesto. However, there are services departing from Brno station and arriving at Nové Mesto station via Bratislava, Autobusová stanica Mlynské Nivy. The journey, including transfers, takes approximately 2h 31m.
Brno to Nové Mesto bus services, operated by FlixBus, depart from Brno station.
Brno to Nové Mesto bus services, operated by FlixBus, arrive at Bratislava, Autobusová stanica Mlynské Nivy station.
Book your Brno to Nové Mesto bus tickets online with FlixBus and Arriva Slovensko.
The distance between Brno and Nové Mesto is 120.8 km. The road distance is 136 km.
FlixBus operates a bus from Brno to Bratislava, Autobusová stanica Mlynské Nivy hourly. Tickets cost €11–20 and the journey takes 1h 45m.