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Brno to Pilsen buses

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Trip Overview

The average bus between Brno and Pilsen takes 4h 25m and the fastest bus takes 3h 56m. There is at least one bus per day from Brno to Pilsen. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 25m
Duration
300 km
Distance
Kč 450
Average price
Once daily
Frequency

Brno to Pilsen bus times

Buses run once daily between Brno and Pilsen. The earliest departure is at 2:40 PM in the afternoon, and the last departure from Brno is at 11:59 PM which arrives into Pilsen at 3:55 AM. All services run direct with no transfers required, and take on average 4h 25m. The schedules shown below are for the next available departures.

Departing Monday, November 2, 2026

  •  → 

    bus bus 4h 55m • Direct

Departing Wednesday, November 4, 2026

  •  → 

    Arrives next day

    bus bus 3h 56m • Direct

Departing Thursday, November 5, 2026

  •  → 

    bus bus 4h 55m • Direct
  •  → 

    Arrives next day

    bus bus 3h 56m • Direct

Departing Friday, November 6, 2026

  •  → 

    bus bus 4h 55m • Direct
  •  → 

    Arrives next day

    bus bus 3h 56m • Direct

Departing Saturday, November 7, 2026

  •  → 

    bus bus 4h 55m • Direct
  •  → 

    Arrives next day

    bus bus 3h 56m • Direct

Departing Sunday, November 8, 2026

  •  → 

    bus bus 4h 55m • Direct
  •  → 

    Arrives next day

    bus bus 3h 56m • Direct

Frequently asked questions

Want to know about travelling from Brno to Pilsen? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Brno to Pilsen.ExpandLaunch map view
  • Distance: 299.7 km
  • Duration: 4h 25m

What companies run services between Brno, Czechia and Pilsen, Czechia?

FlixBus operates a bus from Brno to Plzeň once daily. Tickets cost Kč 650–1,000 and the journey takes 3h 56m. Four other operators also service this route.

Operators