The average bus between Brookline and Plymouth takes 1h 25m and the fastest bus takes 1h 15m. There is a bus service every few hours from Brookline to Plymouth. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Brookline and Plymouth. The earliest departure is at 5:59 AM in the morning, and the last departure from Brookline is at 11:22 PM which arrives into Plymouth at 12:40 AM. All services require a transfer at Essex St @ Atlantic Ave and take an average of 1h 25m. The schedules shown below are for the next available departures.

1h 15m • 1 change

1h 27m • 1 change

1h 23m • 1 change

1h 27m • 1 change

1h 21m • 1 change

1h 22m • 1 change

1h 22m • 1 change

1h 21m • 1 change

1h 18m • 1 change

1h 15m • 1 change

1h 17m • 1 change

1h 20m • 1 change
Want to know about travelling from Brookline to Plymouth? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Brookline to Plymouth. However, there are services departing from Brookline station and arriving at Plymouth station via Essex St @ Atlantic Ave. The journey, including transfers, takes approximately 1h 25m.
Brookline to Plymouth bus services, operated by MBTA, depart from Nubian station.
Brookline to Plymouth bus services, operated by MBTA, arrive at Park & Ride Lot, Ex 13 Info. Ctr. station.
The distance between Brookline and Plymouth is 55.9 km. The road distance is 69 km.
You can take a bus from Nubian to Park & Ride Lot, Ex 13 Info. Ctr. via Essex St @ Atlantic Ave and Boston South Buses in around 1h 58m.