The average bus between Brooklyn and Syracuse takes 7h 12m and the fastest bus takes 6h 24m. The bus service runs several times per day from Brooklyn to Syracuse. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Brooklyn and Syracuse. The earliest departure is at 6:25 AM in the morning, and the last departure from Brooklyn is at 4:05 PM which arrives into Syracuse at 1:15 AM. All services require a transfer at 42 St-Times Square and take an average of 7h 12m. The schedules shown below are for the next available departures.

6h 28m • 1 change

6h 24m • 1 change

6h 45m • 1 change

6h 25m • 1 change

7h 10m • 1 change

7h 10m • 1 change

7h 15m • 1 change

7h 10m • 1 change

6h 28m • 1 change

6h 24m • 1 change

6h 45m • 1 change

6h 25m • 1 change
Want to know about travelling from Brooklyn to Syracuse? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Brooklyn to Syracuse. However, there are services departing from Brooklyn station and arriving at Syracuse station via Syracuse Bus Station station. The journey, including transfers, takes approximately 7h 12m.
Brooklyn to Syracuse bus services, operated by MTA Bus Company, depart from Port Authority Bus Terminal station.
Brooklyn to Syracuse bus services, operated by MTA Bus Company, arrive at Syracuse Bus Station.
The distance between Brooklyn and Syracuse is 322.8 km. The road distance is 435 km.
Greyhound USA operates a bus from Port Authority Bus Terminal to Syracuse Bus Station every 2 hours. Tickets cost $35–75 and the journey takes 4h 45m. Trailways also services this route 4 times a day.