The average bus between Brussels-South Station and Avignon takes 18h 52m and the fastest bus takes 14h 55m. The bus service runs several times per day from Brussels-South Station to Avignon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Brussels-South Station and Avignon. The earliest departure is at 6:05 AM in the morning, and the last departure from Brussels-South Station is at 8:15 PM which arrives into Avignon at 11:10 AM. All services require a transfer, and take on average 18h 52m. The schedules shown below are for the next available departures.
Arrives next day

22h 50m • 1 change
Arrives next day

14h 55m • 1 change
Arrives next day

22h 50m • 1 change
Arrives next day

14h 55m • 1 change
Arrives next day

22h 50m • 1 change
Arrives next day

14h 55m • 1 change
Want to know about travelling from Brussels-South Station to Avignon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Brussels-South Station to Avignon. However, there are services departing from Brussels-South Station station and arriving at Avignon station via Valence. The journey, including transfers, takes approximately 18h 52m.
Brussels-South Station to Avignon bus services, operated by FlixBus, depart from Brussels South station.
Brussels-South Station to Avignon bus services, operated by FlixBus, arrive at Avignon station.
Book your Brussels-South Station to Avignon bus tickets online with FlixBus and BlaBlaCar Bus.
The distance between Brussels-South Station and Avignon is 766.6 km. The road distance is 1,029 km.
You can take a bus from Brussels South to Avignon via Valence in around 14h 45m.