The average bus between Brussels-South Station and Karlsruhe takes 7h 35m and the fastest bus takes 6h 50m. The bus service runs several times per day from Brussels-South Station to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Brussels-South Station and Karlsruhe. The earliest departure is at 5:35 PM in the evening, and the last departure from Brussels-South Station is at 11:35 PM which arrives into Karlsruhe at 6:25 AM. All services require a transfer, and take on average 7h 35m. The schedules shown below are for the next available departures.
Arrives next day

8h 15m • 1 change
Arrives next day

6h 50m • 1 change
Arrives next day

8h 15m • 1 change
Arrives next day

6h 50m • 1 change
Arrives next day

8h 15m • 1 change
Arrives next day

6h 50m • 1 change
Arrives next day

8h 15m • 1 change
Arrives next day

6h 50m • 1 change
Want to know about travelling from Brussels-South Station to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Brussels-South Station to Karlsruhe. However, there are services departing from Brussels-South Station station and arriving at Karlsruhe station via Strasbourg - L'Étoile Park Bus Station station. The journey, including transfers, takes approximately 7h 35m.
Brussels-South Station to Karlsruhe bus services, operated by BlaBlaCar Bus, depart from Brussels - Midi Train Station.
Brussels-South Station to Karlsruhe bus services, operated by BlaBlaCar Bus, arrive at Karlsruhe central train station.
Book your Brussels-South Station to Karlsruhe bus tickets online with BlaBlaCar Bus and FlixBus.
The distance between Brussels-South Station and Karlsruhe is 355.1 km. The road distance is 521 km.
You can take a bus from Brussels - Midi Train Station to Karlsruhe central train station via Strasbourg in around 8h 7m.