The average bus between Brussels and Anne Frankhuis takes 3h 53m and the fastest bus takes 3h 3m. There is a bus service every few hours from Brussels to Anne Frankhuis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Brussels and Anne Frankhuis. The earliest departure is at 3:45 AM at night, and the last departure from Brussels is at 9:45 PM which arrives into Anne Frankhuis at 6:15 AM. All services require a transfer at Amsterdam Sloterdijk and take an average of 3h 53m. The schedules shown below are for the next available departures.

4h 25m • 1 change

4h 3m • 1 change

3h 10m • 1 change

3h 10m • 1 change

4h 16m • 1 change

4h 1m • 1 change

3h 8m • 1 change

3h 9m • 1 change

4h 31m • 1 change

4h 1m • 1 change

3h 18m • 1 change

3h 3m • 1 change

4h 25m • 1 change

4h 3m • 1 change

3h 10m • 1 change

3h 10m • 1 change
Want to know about travelling from Brussels to Anne Frankhuis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Brussels to Anne Frankhuis. However, there are services departing from Brussels station and arriving at Anne Frankhuis station via Amsterdam Sloterdijk. The journey, including transfers, takes approximately 3h 53m.
Brussels to Anne Frankhuis bus services, operated by FlixBus, depart from Brussels-North train station.
Brussels to Anne Frankhuis bus services, operated by FlixBus, arrive at Amsterdam Sloterdijk station.
The distance between Brussels and Anne Frankhuis is 173.5 km. The road distance is 213 km.
FlixBus operates a bus from Brussels-North train station to Amsterdam Sloterdijk hourly. Tickets cost €17–30 and the journey takes 2h 45m.