The average bus between Brussels and Leiden Centraal takes 4h 11m and the fastest bus takes 3h 43m. The bus service runs several times per day from Brussels to Leiden Centraal. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Brussels and Leiden Centraal. The earliest departure is at 3:45 AM at night, and the last departure from Brussels is at 7:15 PM which arrives into Leiden Centraal at 11:14 PM. All services require a transfer at The Hague and take an average of 4h 11m. The schedules shown below are for the next available departures.

3h 43m • 1 change

4h 28m • 1 change

4h 28m • 1 change

6h 28m • 1 change

3h 58m • 1 change

3h 43m • 1 change

4h 28m • 1 change

4h 28m • 1 change

3h 58m • 1 change

3h 43m • 1 change

4h 28m • 1 change

6h 28m • 1 change

3h 58m • 1 change

3h 43m • 1 change

4h 28m • 1 change

6h 28m • 1 change

3h 58m • 1 change

3h 43m • 1 change

4h 28m • 1 change

4h 28m • 1 change
Want to know about travelling from Brussels to Leiden Centraal? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Brussels to Leiden Centraal. However, there are services departing from Brussels station and arriving at Leiden Centraal station via The Hague. The journey, including transfers, takes approximately 4h 11m.
Brussels to Leiden Centraal bus services, operated by FlixBus, depart from Brussels-North train station.
Brussels to Leiden Centraal bus services, operated by FlixBus, arrive at Leiden, Leiden Centraal station.
The distance between Brussels and Leiden Centraal is 146.5 km. The road distance is 189 km.
You can take a bus from Brussels-North train station to Leiden, Leiden Centraal via The Hague and Den Haag, Den Haag Centraal in around 4h 27m.