The average bus between Brussels and Letterhoutem takes 2h 15m and the fastest bus takes 1h 38m. There is a bus service every few hours from Brussels to Letterhoutem. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Brussels and Letterhoutem. The earliest departure is at 5:34 AM in the morning, and the last departure from Brussels is at 11:25 PM which arrives into Letterhoutem at 6:28 AM. All services require a transfer, and take on average 2h 15m. The schedules shown below are for the next available departures.

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1h 49m • 1 changeWant to know about travelling from Brussels to Letterhoutem? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Brussels to Letterhoutem. However, there are services departing from Brussel IJzer station and arriving at Letterhoutem Kerkstraat station via Aalst Station perron 5. The journey, including transfers, takes approximately 2h 15m.
Brussels to Letterhoutem bus services, operated by De Lijn, depart from Brussel IJzer station.
Brussels to Letterhoutem bus services, operated by De Lijn, arrive at Letterhoutem Kerkstraat station.
The distance between Brussels and Letterhoutem is 33.9 km. The road distance is 39 km.
You can take a bus from Brussel IJzer to Letterhoutem Kerkstraat via Aalst Station perron 3 in around 2h 11m.