The average bus between Brussels and Lisse takes 5h 4m and the fastest bus takes 4h 1m. The bus service runs several times per day from Brussels to Lisse. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Brussels and Lisse. The earliest departure is at 3:45 AM at night, and the last departure from Brussels is at 9:45 PM which arrives into Lisse at 6:10 AM. All services require a transfer at Amsterdam Sloterdijk and take an average of 5h 4m. The schedules shown below are for the next available departures.


5h 25m • 2 changes


5h 10m • 2 changes


4h 10m • 2 changes


4h 10m • 2 changes


5h 54m • 2 changes


5h 39m • 2 changes


4h 39m • 2 changes


4h 14m • 2 changes


5h 56m • 2 changes


5h 41m • 2 changes


4h 41m • 2 changes


4h 16m • 2 changes


5h 25m • 2 changes


5h 10m • 2 changes


4h 10m • 2 changes


4h 10m • 2 changes
Want to know about travelling from Brussels to Lisse? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Brussels to Lisse. However, there are services departing from Brussels station and arriving at Lisse station via Amsterdam Sloterdijk. The journey, including transfers, takes approximately 5h 4m.
Brussels to Lisse bus services, operated by FlixBus, depart from Brussels-North train station.
Brussels to Lisse bus services, operated by FlixBus, arrive at Amsterdam Sloterdijk station.
The distance between Brussels and Lisse is 157.4 km. The road distance is 245 km.
FlixBus operates a bus from Brussels-North train station to Amsterdam Sloterdijk hourly. Tickets cost €15–26 and the journey takes 2h 45m.