The average bus between Brussels and Opio takes 23h 4m and the fastest bus takes 21h 18m. The bus service runs several times per day from Brussels to Opio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Brussels and Opio. The earliest departure is at 6:05 AM in the morning, and the last departure from Brussels is at 10:15 PM which arrives into Opio at 8:31 PM. All services require a transfer at Nice and take an average of 23h 4m. The schedules shown below are for the next available departures.
Arrives next day


24h 31m • 2 changes
Arrives next day


21h 18m • 2 changes
Arrives next day


24h 31m • 2 changes
Arrives next day


21h 18m • 2 changes
Arrives next day


24h 31m • 2 changes
Arrives next day


21h 18m • 2 changes
Want to know about travelling from Brussels to Opio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Brussels to Opio. However, there are services departing from Brussels station and arriving at Opio station via Nice. The journey, including transfers, takes approximately 23h 4m.
Brussels to Opio bus services, operated by BlaBlaCar Bus, depart from Brussels-North train station.
Brussels to Opio bus services, operated by BlaBlaCar Bus, arrive at Nice station.
The distance between Brussels and Opio is 822.8 km. The road distance is 1,215 km.
FlixBus operates a bus from Brussels-North train station to Nice 5 times a week. Tickets cost €100–170 and the journey takes 16h 35m.