The average bus between Brussels and Santes takes 3h 3m and the fastest bus takes 2h 44m. The bus service runs several times per day from Brussels to Santes. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Brussels and Santes. The earliest departure is at 2:35 AM at night, and the last departure from Brussels is at 6:50 PM which arrives into Santes at 9:34 PM. All services require a transfer at Lille and take an average of 3h 3m. The schedules shown below are for the next available departures.


3h 33m • 2 changes


2h 47m • 2 changes


3h 2m • 2 changes


3h 1m • 2 changes


3h 33m • 2 changes


2h 47m • 2 changes


3h 2m • 2 changes


3h 1m • 2 changes


3h 33m • 2 changes


2h 47m • 2 changes


3h 2m • 2 changes


3h 1m • 2 changes


3h 33m • 2 changes


2h 47m • 2 changes


3h 2m • 2 changes


3h 1m • 2 changes


3h 33m • 2 changes


2h 47m • 2 changes


3h 2m • 2 changes


3h 1m • 2 changes


3h 29m • 2 changes


2h 44m • 2 changes


2h 46m • 2 changes


3h 6m • 2 changes
Want to know about travelling from Brussels to Santes? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Brussels to Santes. However, there are services departing from Brussels station and arriving at Santes station via Lille. The journey, including transfers, takes approximately 3h 3m.
Brussels to Santes bus services, operated by BlaBlaCar Bus, depart from Brussels-North train station.
Brussels to Santes bus services, operated by BlaBlaCar Bus, arrive at Lille station.
The distance between Brussels and Santes is 102 km. The road distance is 133 km.
FlixBus operates a bus from Brussels-North train station to Lille hourly. Tickets cost €8–14 and the journey takes 1h 35m.