The average bus between Brussels and Santes takes 3h 7m and the fastest bus takes 2h 43m. The bus service runs several times per day from Brussels to Santes. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Brussels and Santes. The earliest departure is at 2:35 AM at night, and the last departure from Brussels is at 6:50 PM which arrives into Santes at 9:34 PM. All services require a transfer at Lille and take an average of 3h 7m. The schedules shown below are for the next available departures.


3h 33m • 2 changes

2h 47m • 2 changes

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3h 29m • 2 changes

2h 44m • 2 changes

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3h 6m • 2 changes

7h • 2 changes

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3h 10m • 2 changes

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3h 33m • 2 changes

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3h 1m • 2 changesWant to know about travelling from Brussels to Santes? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Brussels to Santes. However, there are services departing from Brussels station and arriving at Santes station via Lille. The journey, including transfers, takes approximately 3h 7m.
Brussels to Santes bus services, operated by FlixBus, depart from Brussels-North train station.
Brussels to Santes bus services, operated by FlixBus, arrive at Santes Eglise station.
The distance between Brussels and Santes is 102 km. The road distance is 129 km.
You can take a bus from Brussels-North train station to Santes Eglise via Lille, Gare Lille Flandres, Chu - Eurasanté, and Chu - Eurasanté in around 2h 52m.