The average bus between Brussels and Sint-Niklaas takes 2h 40m and the fastest bus takes 2h 17m. The bus service runs several times per day from Brussels to Sint-Niklaas. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Brussels and Sint-Niklaas. The earliest departure is at 5:34 AM in the morning, and the last departure from Brussels is at 7:11 PM which arrives into Sint-Niklaas at 9:45 PM. All services require a transfer, and take on average 2h 40m. The schedules shown below are for the next available departures.

2h 40m • 1 change
2h 50m • 1 change
2h 37m • 1 change
2h 50m • 1 changeWant to know about travelling from Brussels to Sint-Niklaas? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Brussels to Sint-Niklaas. However, there are services departing from Brussels station and arriving at Sint-Niklaas station via Aalst Station perron 5 station. The journey, including transfers, takes approximately 2h 40m.
Brussels to Sint-Niklaas bus services, operated by De Lijn, depart from Brussel IJzer station.
Brussels to Sint-Niklaas bus services, operated by De Lijn, arrive at Sint-Niklaas Grote Markt station.
The distance between Brussels and Sint-Niklaas is 37.8 km. The road distance is 114 km.
You can take a bus from Brussel IJzer to Sint-Niklaas Grote Markt via Aalst Station perron 4 in around 2h 37m.