The average bus between Brussels and Southampton takes 13h 6m and the fastest bus takes 12h 40m. The bus service runs several times per day from Brussels to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Brussels and Southampton. The earliest departure is at 12:10 AM at night, and the last departure from Brussels is at 11:20 PM which arrives into Southampton at 11:20 AM. All services require a transfer, and take on average 13h 6m. The schedules shown below are for the next available departures.

13h 20m • 1 change
12h 55m • 1 changeArrives next day

13h 45m • 1 change
13h 20m • 1 change
12h 55m • 1 changeArrives next day

13h 45m • 1 change
13h 20m • 1 change
12h 55m • 1 changeArrives next day

13h 15m • 1 change
12h 40m • 1 change
12h 55m • 1 changeArrives next day

13h 15m • 1 changeWant to know about travelling from Brussels to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Brussels to Southampton. However, there are services departing from Brussels station and arriving at Southampton station via London Victoria. The journey, including transfers, takes approximately 13h 6m.
Brussels to Southampton bus services, operated by FlixBus, depart from Brussels-North train station.
Brussels to Southampton bus services, operated by FlixBus, arrive at Coach Station.
Book your Brussels to Southampton bus tickets online with FlixBus and National Express.
The distance between Brussels and Southampton is 403.6 km. The road distance is 533 km.
You can take a bus from Brussels-North train station to Coach Station via London Victoria in around 11h 57m.