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Buffalo to Cleveland Clinic buses

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Trip Overview

The bus between Buffalo and Cleveland Clinic takes 16h 48m. The bus runs, on average, 4 times per week from Buffalo to Cleveland Clinic. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

16h 48m
Duration
216 mi
Distance
$52
Average price
4 times a week
Frequency

Buffalo to Cleveland Clinic bus times

Buses run 4 times a week between Buffalo and Cleveland Clinic. The service departs Buffalo at 2:20 PM in the afternoon, which arrives into Cleveland Clinic at 07:08:00. All services require a transfer at Cleveland Bus Station and take an average of 16h 48m. The schedules shown below are for the next available departures.

Departing Sunday, November 1, 2026

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    Arrives next day

    Barons BusMETRO RTA16h 48m • 1 change

Departing Monday, November 2, 2026

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    Arrives next day

    Barons BusMETRO RTA16h 48m • 1 change

Departing Tuesday, November 3, 2026

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    Arrives next day

    Barons BusMETRO RTA16h 48m • 1 change

Departing Wednesday, November 4, 2026

  •  → 

    Arrives next day

    Barons BusMETRO RTA16h 48m • 1 change

Frequently asked questions

Want to know about travelling from Buffalo to Cleveland Clinic? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Buffalo to Cleveland Clinic.ExpandLaunch map view
  • Distance: 215.6 mi
  • Duration: 16h 48m

What companies run services between Buffalo, NY, USA and Cleveland Clinic, OH, USA?

Greyhound USA operates a bus from Buffalo to Cleveland Bus Station twice daily. Tickets cost $35–55 and the journey takes 3h 15m.

Operators