The bus between Buffalo and La Crosse takes 28h 45m. The bus runs, on average, 6 times per week from Buffalo to La Crosse. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 6 times a week between Buffalo and La Crosse. The earliest departure is at 7:55 AM in the morning, and the last departure from Buffalo is at 7:55 AM which arrives into La Crosse at 12:40 PM. All services require a transfer at Cleveland Bus Station and take an average of 28h 45m. The schedules shown below are for the next available departures.
Want to know about travelling from Buffalo to La Crosse? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Buffalo to La Crosse. However, there are services departing from Buffalo station and arriving at La Crosse station via Cleveland Bus Station station. The journey, including transfers, takes approximately 28h 45m.
Buffalo to La Crosse bus services, operated by Greyhound USA, depart from Buffalo station.
Buffalo to La Crosse bus services, operated by Greyhound USA, arrive at La Crosse station.
Book your Buffalo to La Crosse bus tickets online with Greyhound USA and Jefferson Lines.
The distance between Buffalo and La Crosse is 1,003.8 km. The road distance is 1,346 km.
You can take a bus from Buffalo to La Crosse via Cleveland Bus Station, Chicago Bus Station, Milwaukee Intermodal Station, and Milwaukee in around 19h.
