The average bus between Buffalo and Le Moyne College takes 4h 52m and the fastest bus takes 3h 46m. The bus service runs several times per day from Buffalo to Le Moyne College. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Buffalo and Le Moyne College. The earliest departure is at 12:55 AM at night, and the last departure from Buffalo is at 8:45 PM which arrives into Le Moyne College at 5:16 AM. All services require a transfer at Regional Transportation Center and take an average of 4h 52m. The schedules shown below are for the next available departures.


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3h 56m • 2 changes


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4h 36m • 2 changes


3h 56m • 2 changes


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3h 56m • 2 changes


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3h 56m • 2 changes
Want to know about travelling from Buffalo to Le Moyne College? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Buffalo to Le Moyne College. However, there are services departing from Buffalo station and arriving at Le Moyne College station via Syracuse Bus Station station. The journey, including transfers, takes approximately 4h 52m.
Buffalo to Le Moyne College bus services, operated by Greyhound USA, depart from Buffalo station.
Buffalo to Le Moyne College bus services, operated by Greyhound USA, arrive at Syracuse Bus Station.
The distance between Buffalo and Le Moyne College is 227.7 km. The road distance is 268 km.
FlixBus-us operates a bus from Buffalo to Syracuse Bus Station every 4 hours, and the journey takes 2h 50m. Five other operators also service this route.