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Buffalo to Lewes buses

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Trip Overview

The average bus between Buffalo and Lewes takes 20h 56m and the fastest bus takes 16h 55m. The bus runs, on average, 4 times per week from Buffalo to Lewes. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

20h 56m
Duration
603 mi
Distance
$117
Average price
4 times a week
Frequency

Buffalo to Lewes bus times

Buses run 4 times a week between Buffalo and Lewes. The earliest departure is at 10:30 AM in the morning, and the last departure from Buffalo is at 11:00 PM which arrives into Lewes at 6:25 PM. All services require a transfer at Newark Penn Station and take an average of 20h 56m. The schedules shown below are for the next available departures.

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    Flixbus USAGreyhound USADART First StateDART First State23h 54m • 3 changes
  •  → 

    Arrives next day

    Flixbus USAGreyhound USADART First StateDART First State19h 25m • 3 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    Flixbus USAGreyhound USADART First StateDART First State23h 29m • 3 changes
  •  → 

    Arrives next day

    Flixbus USAGreyhound USADART First StateDART First State16h 55m • 3 changes

Frequently asked questions

Want to know about travelling from Buffalo to Lewes? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Buffalo to Lewes.ExpandLaunch map view
  • Distance: 602.6 mi
  • Duration: 20h 56m

What companies run services between Buffalo, NY, USA and Lewes, DE, USA?

You can take a bus from Buffalo to Savannah Rd @ 3Rd St via Newark Penn Station, Wilmington Bus Station, Wilmington Tc, and Lewes Transit Center in around 14h 50m.

Operators