Rome2Rio

Buffalo to Manchester buses

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Trip Overview

The bus between Buffalo and Manchester takes 18h 5m. The bus runs, on average, 6 times per week from Buffalo to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

18h 5m
Duration
812 mi
Distance
$158
Average price
6 times a week
Frequency

Buffalo to Manchester bus times

Buses run 6 times a week between Buffalo and Manchester. The service departs Buffalo at 2:20 PM in the afternoon, which arrives into Manchester at 07:25:00. All services require a transfer at Cincinnati and take an average of 18h 5m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

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    Arrives next day

    Barons BusGreyhound USA18h 5m • 1 change

Departing Wednesday, November 11, 2026

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    Arrives next day

    Barons BusGreyhound USA18h 5m • 1 change

Departing Thursday, November 12, 2026

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    Arrives next day

    Barons BusGreyhound USA18h 5m • 1 change

Departing Friday, November 13, 2026

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    Arrives next day

    Barons BusGreyhound USA18h 5m • 1 change

Departing Saturday, November 14, 2026

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    Arrives next day

    Barons BusGreyhound USA18h 5m • 1 change

Departing Sunday, November 15, 2026

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    Arrives next day

    Barons BusGreyhound USA18h 5m • 1 change

Frequently asked questions

Want to know about travelling from Buffalo to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Buffalo to Manchester.ExpandLaunch map view
  • Distance: 812 mi
  • Duration: 18h 5m

What companies run services between Buffalo, NY, USA and Manchester, TN, USA?

You can take a bus from Buffalo to Manchester via Cincinnati and Cincinnati Bus Station in around 20h 25m.

Operators