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Buffalo to Port Saint Lucie buses

Find Transport to Port Saint Lucie

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Trip Overview

The average bus between Buffalo and Port Saint Lucie takes 2d and the fastest bus takes 44h 22m. The bus runs, on average, 3 times per week from Buffalo to Port Saint Lucie. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d
Duration
1,704 mi
Distance
$338
Average price
3 times a week
Frequency

Buffalo to Port Saint Lucie bus times

Buses run 3 times a week between Buffalo and Port Saint Lucie. The service departs Buffalo at 10:30 AM in the morning, which arrives into Port Saint Lucie at 06:52:00. All services require a transfer at Newark Penn Station and take an average of 2d. The schedules shown below are for the next available departures.

Departing Monday, November 9, 2026

  •  → 

    Arrives +2 days

    Flixbus USAFlixbus USAFlixbus USAArea Regional Transit St Lucie44h 22m • 3 changes

Departing Tuesday, November 10, 2026

  •  → 

    Arrives +2 days

    Flixbus USAFlixbus USAFlixbus USAArea Regional Transit St Lucie44h 22m • 3 changes

Frequently asked questions

Want to know about travelling from Buffalo to Port Saint Lucie? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Buffalo to Port Saint Lucie.ExpandLaunch map view
  • Distance: 1,704.1 mi
  • Duration: 2d

What companies run services between Buffalo, NY, USA and Port Saint Lucie, FL, USA?

You can take a bus from Buffalo to SW PSL Blvd & SE Bayshore Blvd via Newark Penn Station, West Palm Beach Bus Station, WPB ITC at BAY D, and SW Gatlin Blvd & SW Brescia St in around 35h 44m.

Operators