The average bus between Buffalo and Saint Paul takes 24h 21m and the fastest bus takes 22h 50m. The bus service runs several times per day from Buffalo to Saint Paul. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Buffalo and Saint Paul. The earliest departure is at 7:55 AM in the morning, and the last departure from Buffalo is at 11:05 PM which arrives into Saint Paul at 11:45 PM. All services require a transfer at Cleveland Bus Station and take an average of 24h 21m. The schedules shown below are for the next available departures.
Arrives next day


21h 50m • 2 changes
Arrives next day


24h 40m • 2 changes
Arrives next day


21h 50m • 2 changes
Arrives next day


24h 40m • 2 changes
Arrives next day


21h 50m • 2 changes
Arrives next day


24h 40m • 2 changes
Want to know about travelling from Buffalo to Saint Paul? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Buffalo to Saint Paul. However, there are services departing from Buffalo station and arriving at Saint Paul station via Cleveland Bus Station station. The journey, including transfers, takes approximately 24h 21m.
Buffalo to Saint Paul bus services, operated by Greyhound USA, depart from Buffalo station.
Buffalo to Saint Paul bus services, operated by Greyhound USA, arrive at Saint Paul Union Depot station.
Book your Buffalo to Saint Paul bus tickets online with Greyhound USA.
The distance between Buffalo and Saint Paul is 1,159.8 km. The road distance is 1,548 km.
You can take a bus from Buffalo to Saint Paul Union Depot via Cleveland Bus Station and Chicago Bus Station in around 20h 25m.